
bioRxiv (pronounced "bio-archive") is an open-access preprint repository specifically dedicated to the biological sciences. It is a platform where researchers share their results (papers) with the scientific community before manuscripts undergo formal peer review or publication in an academic journal.
OpenRxiv, a non-profit organization focused on science communication, operates the service, which Cold Spring Harbor Laboratory founded in 2013.
The repository allows authors to post their draft manuscripts across a wide array of life science disciplines.
When submitting a paper, researchers assign it to a specific category, ranging from Biochemistry and Cell Biology to Neuroscience, Genomics, and Evolutionary Biology.
The platform classifies submissions into three distinct categories:
- "New results" describe novel advances.
- "Confirmatory results" essentially replicate previously published work.
- "Contradictory results" replicate earlier experiments but lead to opposing conclusions.
This structure allows readers to quickly understand the context of a pre-publication.
Although manuscripts posted on bioRxiv do not undergo peer review or editorial revision prior to online publication, they are subject to a preliminary screening process. This check aims to detect offensive or non-scientific content, plagiarism, and material that could pose a health risk. Once posted online, the article is assigned a Digital Object Identifier (DOI), making it immediately citable and permanently part of the scientific record; it cannot be withdrawn after publication. The platform fosters community interaction by allowing readers to post public comments on preprints. Authors also have the option to submit revised versions of their manuscripts at any time, provided the article has not yet been formally accepted by a journal.
bioRxiv aims to accelerate the pace of scientific discovery by enabling the rapid dissemination of results, thereby offering researchers the opportunity to receive feedback on their work and establish priority for their discoveries without waiting for the traditional publication cycle that van be months or years.
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